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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for NuRD complex
Gene ontology ID
GO:0016581
Definition
An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins
Synonyms
1. Mi-2 complex
2. NRD complex
3. nucleosome remodeling and histone deacetylation complex
References
1. PMID 10589671
2. PMID 11743021
3. PMID 17289569
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
cellular_component is a
cellular anatomical entity is a
chromatin is a463 BRENDA localization in branch, click for list of all
nuclear chromatin is a9 BRENDA localization in branch, click for list of all
SWI/SNF superfamily-type complex part of
CHD-type complex is a
NuRD complex is a