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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for TCR signalosome
Gene ontology ID
GO:0036398
Definition
A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology
Synonyms
1. LAT signalosome
2. linker for activation of T cells signalosome
References
1. GOC: krc
2. PMID 17534068
3. PMID 20107804
4. PMID 22426112
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
cellular_component is a
cellular anatomical entity is a
cell periphery is a651 BRENDA localization in branch, click for list of all
plasma membrane part of611 BRENDA localization in branch, click for list of all
plasma membrane protein complex part of49 BRENDA localization in branch, click for list of all
plasma membrane signaling receptor complex is a
T cell receptor complex is a
TCR signalosome