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Gene ontology
Version 2014-12-22
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Details for Dom34-Hbs1 complex
Gene ontology ID
GO:1990533
Definition
A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay
References
1. GOC: mcc
2. PMID 20890290
3. PMID 21102444
4. PMID 21448132
5. PMID 22503425
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