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Version 2014-12-22
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Details for nuclear pore central transport channel
Gene ontology ID
The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153
1. karyopherin docking complex
2. nuclear pore central channel
3. nuclear pore central plug
4. nuclear pore transport channel
1. GOC: dgf
2. PMID 18046406
3. PMID 19524430
4. PMID 20947011
5. PMID 22419078
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