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Gene ontology
Version 2014-12-22
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Details for apoptosome
apoptosome
Gene ontology ID
GO:0043293
Definition
A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms
References
1. GOC: mtg apoptosis
2. PMID 10428850
3. PMID 11406413
4. PMID 12176339
5. PMID 15189137
6. Wikipedia: Apoptosome
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