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Version 2014-12-22
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Details for CFTR-NHERF-ezrin complex
Gene ontology ID
GO:0034662
Definition
A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity
References
1. PMID 16129695
2. PMID 16798722
3. PMID 16926444
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