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Gene ontology
Version 2014-12-22
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Details for CAF-1 complex
Gene ontology ID
GO:0033186
Definition
A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48
Comment
In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.
Synonyms
1. chromatin assembly factor 1 complex
References
1. PMID 17065558
2. PMID 17083276
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Gene ontology