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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for DNA recombinase mediator complex
Gene ontology ID
GO:0033061
Definition
A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA
Comment
Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly.
References
1. GOC: elh
2. GOC: mah
3. GOC: vw
4. InterPro: IPR003488
5. PMID 12912992
Legend
is an element of the parent element
is a part of the parent element
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derives from the parent element
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Gene ontology