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Gene ontology
Version 2014-12-22
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Details for retromer, tubulation complex
Gene ontology ID
GO:0030905
Definition
The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6
Synonyms
1. heterodimeric membrane-deforming retromer subcomplex
2. retromer complex, outer shell
3. SNX-BAR dimer
References
1. GOC: bf
2. PMID 26220253
3. PMID 9700157
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