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Gene ontology
Version 2014-12-22
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Details for Type III site-specific deoxyribonuclease complex
Gene ontology ID
GO:0019813
Definition
A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell
References
1. PMID 12654995
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