Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
Details for excinuclease repair complex
Gene ontology ID
GO:0009380
Definition
Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap
Synonyms
1. excinuclease ABC complex
2. UvrABC excinuclease complex
References
1. GOC: mah
2. GOC: mlg
3. PMID 12145219
4. PMID 15192705
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology