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Gene ontology
Version 2014-12-22
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Details for COP9 signalosome
COP9 signalosome
Gene ontology ID
GO:0008180
Definition
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome
References
1. PMID 11019806
2. PMID 12186635
3. PMID 14570571
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