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Gene ontology
Version 2014-12-22
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Details for nuclear cap binding complex
Gene ontology ID
GO:0005846
Definition
A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export
Comment
Note that this complex can be found in the cytoplasm as well as the nucleus.
Synonyms
1. CBC
2. mRNA cap binding complex
3. NCBP-NIP1 complex
4. snRNA cap binding complex
References
1. PMID 16043498
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Gene ontology