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Version 2014-12-22
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Details for nuclear cap binding complex
Gene ontology ID
GO:0005846
Definition
A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export
Comment
Note that this complex can be found in the cytoplasm as well as the nucleus.
References
1. PMID 16043498
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