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Gene ontology
Version 2014-12-22
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Details for polkadots
Gene ontology ID
GO:0002096
Definition
A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals
Comment
Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.
References
1. PMID 14724296
2. PMID 16495340
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