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Version 2014-12-22
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Details for immunological synapse
Gene ontology ID
GO:0001772
Definition
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction
References
1. GOC: mgi curators
2. PMID 11244041
3. PMID 11376300
4. Wikipedia: Immunological synapse
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