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Version 2014-12-22
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Details for glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
Gene ontology ID
GO:0000506
Definition
An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast
Comment
Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity.
References
1. GOC: kp
2. GOC: rb
3. PMID 10944123
4. PMID 15163411
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