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Gene ontology
Version 2014-12-22
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Details for NuA4 histone acetyltransferase complex
NuA4 histone acetyltransferase complex
Gene ontology ID
GO:0035267
Definition
A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60)
Synonyms
1. TIP60 histone acetylase complex
2. TIP60 histone acetyltransferase complex
References
1. GOC: ecd
2. PMID 10966108
3. PMID 14966270
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