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Version 2014-12-22
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Details for excinuclease repair complex
Gene ontology ID
Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap
1. excinuclease ABC complex
2. UvrABC excinuclease complex
1. GOC: mah
2. GOC: mlg
3. PMID 12145219
4. PMID 15192705
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