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Gene ontology
Version 2014-12-22
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Details for mitotic checkpoint complex, CDC20-MAD2 subcomplex
Gene ontology ID
GO:1990333
Definition
A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20
Comment
An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).
Synonyms
1. CDC20-MAD2 complex
References
1. GOC: bhm
2. PMID 15879521
3. IntAct: EBI-1270646
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Gene ontology