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Gene ontology
Version 2014-12-22
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Details for retromer, tubulation complex
Gene ontology ID
The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6
1. heterodimeric membrane-deforming retromer subcomplex
2. retromer complex, outer shell
3. SNX-BAR dimer
1. GOC: bf
2. PMID 26220253
3. PMID 9700157
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