Details for Bfa1-Bub2 complex
Gene ontology ID
GO:1990334
Definition
A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation
References
1. GOC: bhm
2. PMID 164491873. IntAct: EBI-1271344
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
/
/
at least 1 tissue/ enzyme/ localization link in this branch
/
/
tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology