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Version 2014-12-22
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Details for oxoglutarate dehydrogenase complex
oxoglutarate dehydrogenase complex
Gene ontology ID
GO:0045252
Definition
A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2)
Comment
See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
Synonyms
1. dihydrolipoamide S-succinyltransferase complex
References
1. MetaCyc CPLX66-42
2. PMID 10848975
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