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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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use AND (NOT) or OR
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Details for Bfa1-Bub2 complex
Gene ontology ID
GO:1990334
Definition
A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation
References
1. GOC: bhm
2. PMID 16449187
3. IntAct: EBI-1271344
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is a part of the parent element
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derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
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Gene ontology