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Gene ontology
Version 2014-12-22
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Details for BRCA1-C complex
Gene ontology ID
A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint
1. GOC: mah
2. PMID 15485915
3. PMID 16391231
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