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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for ATF4-CREB1 transcription factor complex
Gene ontology ID
GO:1990589
Definition
Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway
References
1. GOC: bhm
2. PMID 12871976
3. IntAct: EBI-10043081
4. IntAct: EBI-10043332
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