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Gene ontology
Version 2014-12-22
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Details for Ada2/Gcn5/Ada3 transcription activator complex
Gene ontology ID
GO:0005671
Definition
A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues
Comment
In human, this complex is composed of GCN5 or PCAF, ADA2a, ADA3, ZZZ3, ATAC2, SGF29, HCF1, WDR5,YEATS2, NC2-beta, and MBIP.
Synonyms
1. Ada Two-A containing complex
2. Ada-Two-A-containing complex
3. ATAC complex
References
1. PMID 10637607
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