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Gene ontology
Version 2014-12-22
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Details for RNA polymerase I complex
RNA polymerase I complex
Gene ontology ID
GO:0005736
Definition
RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template
Synonyms
1. DNA-directed RNA polymerase I activity
2. DNA-directed RNA polymerase I complex
References
1. GOC: krc
2. GOC: mtg sensu
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