Any feedback?
Please rate this page
(ontology.php)
(0/150)

BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
use AND (NOT) or OR
use AND (NOT) or OR
restrict to BRENDA links:
182 different search results found


Details for anaphase-promoting complex
anaphase-promoting complex
Gene ontology ID
GO:0005680
Definition
A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B
Comment
Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.
Synonyms
1. anaphase promoting complex
2. APC
3. cyclosome
References
1. GOC: jh
2. GOC: vw
3. PMID 10465783
4. PMID 10611969
5. Wikipedia: Anaphase-promoting complex
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
Tree view
Gene ontology