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Gene ontology
Version 2014-12-22
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Details for primosome complex
Gene ontology ID
GO:1990077
Definition
Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart
Synonyms
1. primosome
References
1. GOC: bhm
2. GOC: mah
3. PMID 21856207
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