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Gene ontology
Version 2014-12-22
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Details for DSIF complex
Gene ontology ID
GO:0032044
Definition
A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes
Synonyms
1. 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex
2. DRB sensitivity inducing factor complex
3. Spt4-Spt5 complex
4. Spt5-Spt4 complex
References
1. PMID 12242279
2. PMID 12653964
3. PMID 12676794
4. PMID 16581788
5. PMID 19460865
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