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Gene ontology
Version 2014-12-22
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Details for elongin complex
Gene ontology ID
GO:0070449
Definition
A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits
Comment
See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
Synonyms
1. elongin (SIII) complex
2. transcription elongation factor SIII complex
3. transcription factor B (SIII) complex
References
1. PMID 12676794
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