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Gene ontology
Version 2014-12-22
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Details for eukaryotic translation initiation factor 2B complex
Gene ontology ID
GO:0005851
Definition
A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon
Synonyms
1. eIF-2B
2. eif2B
References
1. PMID 9438375
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
cellular_component is a
cellular anatomical entity is a
cytoplasm is a425 BRENDA localization in branch, click for list of all
eukaryotic translation initiation factor 2B complex part of
plastid part of72 BRENDA localization in branch, click for list of all
Tree view
Gene ontology
biological_process is a
cellular_component is a
cell is a
cellular anatomical entity is a
A band is a698 BRENDA localization in branch, click for list of all
acroblast is a
acrosomal matrix is a695 BRENDA localization in branch, click for list of all
actin body is a
actin cap is a694 BRENDA localization in branch, click for list of all
actin filament branch point is a
actin filament bundle is a
actin fusion focus is a
actomyosin is a688 BRENDA localization in branch, click for list of all
actomyosin contractile ring, distal actin filament layer is a
actomyosin contractile ring, intermediate layer is a
actomyosin contractile ring, proximal layer is a
alae of collagen and cuticulin-based cuticle extracellular matrix is a
annular furrow extracellular matrix is a
annuli extracellular matrix is a
apical complex is a687 BRENDA localization in branch, click for list of all
apical cytoplasm is a
apical lamina of hyaline layer is a
apical part of cell is a682 BRENDA localization in branch, click for list of all
ascus epiplasm is a
assemblon is a
axon collateral is a680 BRENDA localization in branch, click for list of all
axon hillock is a679 BRENDA localization in branch, click for list of all
axon initial segment is a678 BRENDA localization in branch, click for list of all
axonemal basal plate is a
axonemal central apparatus is a
axonemal outer doublet is a
axoneme is a673 BRENDA localization in branch, click for list of all
bacterial biofilm matrix surface is a
bacterial-type flagellum basal body is a
bacterial-type flagellum filament is a
bacterial-type flagellum hook is a
bacterial-type flagellum hook-filament junction is a
basal labyrinth is a
basal layer of collagen and cuticulin-based cuticle extracellular matrix is a
basal part of cell is a
basolateral cytoplasm is a
bilobe structure is a
blood microparticle is a
bridge contact site is a
Casparian strip is a
cell body is a668 BRENDA localization in branch, click for list of all
cell division site is a666 BRENDA localization in branch, click for list of all
cell junction is a661 BRENDA localization in branch, click for list of all
cell leading edge is a
cell periphery is a644 BRENDA localization in branch, click for list of all
cell plate is a467 BRENDA localization in branch, click for list of all
cell pole is a466 BRENDA localization in branch, click for list of all
cell projection is a
cell septum is a459 BRENDA localization in branch, click for list of all
cell surface is a458 BRENDA localization in branch, click for list of all
cell tip is a
cell trailing edge is a
cellular bud is a
central element is a456 BRENDA localization in branch, click for list of all
central plaque of spindle pole body is a
centriolar satellite is a
centrosomal corona is a
chiasma is a455 BRENDA localization in branch, click for list of all
chromatin is a454 BRENDA localization in branch, click for list of all
chromosomal region is a435 BRENDA localization in branch, click for list of all
cnida is a
compact myelin is a429 BRENDA localization in branch, click for list of all
concave side of sperm head is a
cone matrix sheath is a
contact site is a428 BRENDA localization in branch, click for list of all
contractile ring is a427 BRENDA localization in branch, click for list of all
cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a
costamere is a
cytoophidium is a426 BRENDA localization in branch, click for list of all
cytoplasm is a425 BRENDA localization in branch, click for list of all
acetolactate synthase complex part of177 BRENDA localization in branch, click for list of all
acetyl-CoA carboxylase complex part of
acidocalcisome part of176 BRENDA localization in branch, click for list of all
ADPG pyrophosphorylase complex part of
alkyl hydroperoxide reductase complex part of175 BRENDA localization in branch, click for list of all
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) part of
anaerobic ribonucleoside-triphosphate reductase complex part of
anammoxosome part of174 BRENDA localization in branch, click for list of all
anthranilate synthase complex part of173 BRENDA localization in branch, click for list of all
APC-tubulin-IQGAP1 complex part of
Atg1/ULK1 kinase complex part of
Atg12-Atg5-Atg16 complex part of
beta-catenin destruction complex part of
calpain complex part of
carbamoyl-phosphate synthase complex part of
CBM complex part of
Cdc42 GTPase complex part of
citrate lyase complex part of172 BRENDA localization in branch, click for list of all
contractile fiber part of
CRD-mediated mRNA stability complex part of
crystalloid part of163 BRENDA localization in branch, click for list of all
CUGBP1-eIF2 complex part of
Cvt complex part of
cysteine synthase complex part of162 BRENDA localization in branch, click for list of all
cytoplasmic chromosome part of
cytoplasmic cyclin-dependent protein kinase holoenzyme complex part of
cytoplasmic exosome (RNase complex) part of
cytoplasmic microtubule part of
cytoplasmic microtubule bundle part of
cytoplasmic region is a155 BRENDA localization in branch, click for list of all
cytoplasmic ribonucleoprotein granule part of
cytoplasmic transcription factor complex part of
cytoplasmic transcriptional repressor complex part of
cytoplasmic U snRNP body part of
cytoplasmic ubiquitin ligase complex part of
cytoplasmic vesicle part of150 BRENDA localization in branch, click for list of all
cytosol part of128 BRENDA localization in branch, click for list of all
dense body part of
DNA gyrase complex part of
DNA topoisomerase IV complex part of
ectoplasm part of120 BRENDA localization in branch, click for list of all
electron transfer flavoprotein complex part of
endoplasmic reticulum-Golgi intermediate compartment part of
eukaryotic translation elongation factor 1 complex part of
eukaryotic translation initiation factor 2 complex part of
eukaryotic translation initiation factor 2B complex part of
eukaryotic translation initiation factor 3 complex part of
eukaryotic translation initiation factor 4F complex part of
FHF complex part of
fusome part of118 BRENDA localization in branch, click for list of all
G-protein beta/gamma-Btk complex part of
G-protein beta/gamma-Raf-1 complex part of
G-protein beta/gamma-subunit complex part of
glutamate-cysteine ligase complex part of
glutamate-tRNA ligase complex part of
glycerol-3-phosphate dehydrogenase complex part of117 BRENDA localization in branch, click for list of all
glycine cleavage complex part of116 BRENDA localization in branch, click for list of all
glycine reductase complex part of115 BRENDA localization in branch, click for list of all
glycine-tRNA ligase complex part of
glycogen granule part of114 BRENDA localization in branch, click for list of all
glycolate oxidase complex part of
goblet cell theca part of
histone mRNA stem-loop binding complex part of
homodimeric decaprenyl diphosphate synthase complex part of
homomeric SMAD protein complex part of
HSP90-CDC37 chaperone complex part of
hydrogenosome part of113 BRENDA localization in branch, click for list of all
imidazoleglycerol-phosphate synthase complex part of
keratohyalin granule part of
membrane coat part of
methane-oxidizing organelle part of
methionyl glutamyl tRNA synthetase complex part of
methylosome part of
microbody part of108 BRENDA localization in branch, click for list of all
mitochondrial cloud part of99 BRENDA localization in branch, click for list of all
mitochondrion part of98 BRENDA localization in branch, click for list of all
mitosome part of81 BRENDA localization in branch, click for list of all
mitotic spindle assembly checkpoint MAD1-MAD2 complex part of
monolayer-surrounded lipid storage body outer lipid monolayer part of
multi-eIF complex part of
Myo2p-Vac17p-Vac8p transport complex part of
N-terminal protein acetyltransferase complex part of
nascent polypeptide-associated complex part of
neurofilament part of80 BRENDA localization in branch, click for list of all
ooplasm is a79 BRENDA localization in branch, click for list of all
ornithine carbamoyltransferase complex part of
PAN complex part of
Par3-APC-KIF3A complex part of
paraferritin complex part of
perinuclear region of cytoplasm part of
periphagosomal region of cytoplasm part of
PHA granule part of78 BRENDA localization in branch, click for list of all
phagophore part of77 BRENDA localization in branch, click for list of all
phagophore assembly site part of
phenylalanine-tRNA ligase complex part of
phosphoenolpyruvate-dependent sugar phosphotransferase complex part of
phosphopantothenoylcysteine decarboxylase complex part of
phosphoribosylaminoimidazole carboxylase complex part of
phosphorylase kinase complex part of76 BRENDA localization in branch, click for list of all
phragmoplast part of75 BRENDA localization in branch, click for list of all
phragmosome part of74 BRENDA localization in branch, click for list of all
pICln-Sm protein complex part of
pirellulosome part of
plasma membrane-derived chromatophore part of
plastid part of72 BRENDA localization in branch, click for list of all
amyloplast is a39 BRENDA localization in branch, click for list of all
apicoplast is a37 BRENDA localization in branch, click for list of all
chloroplast is a36 BRENDA localization in branch, click for list of all
chromoplast is a19 BRENDA localization in branch, click for list of all
cyanelle is a17 BRENDA localization in branch, click for list of all
etioplast is a15 BRENDA localization in branch, click for list of all
gerontoplast is a11 BRENDA localization in branch, click for list of all
leucoplast is a9 BRENDA localization in branch, click for list of all
nucleomorph part of8 BRENDA localization in branch, click for list of all
phenyloplast is a7 BRENDA localization in branch, click for list of all
plastid envelope part of6 BRENDA localization in branch, click for list of all
plastid mRNA editing complex part of
plastid pyruvate dehydrogenase complex part of4 BRENDA localization in branch, click for list of all
plastid stroma part of3 BRENDA localization in branch, click for list of all
plastid thylakoid part of
plastid-encoded plastid RNA polymerase complex part of
proplastid is a1 BRENDA localization in branch, click for list of all
pyrenoid part of
starch grain part of31 BRENDA localization in branch, click for list of all
pole plasm is a30 BRENDA localization in branch, click for list of all
polkadots part of
polyketide synthase complex part of
preprophase band part of28 BRENDA localization in branch, click for list of all
procentriole part of
procentriole replication complex part of
protein body part of27 BRENDA localization in branch, click for list of all
protein farnesyltransferase complex part of
protein phosphatase type 1 complex part of
protein-N(PI)-phosphohistidine-sugar phosphotransferase complex part of
pyruvate dehydrogenase (lipoamide) phosphatase complex part of
pyruvate dehydrogenase complex part of26 BRENDA localization in branch, click for list of all
Rab-protein geranylgeranyltransferase complex part of
RasGAP-Fyn-Lyn-Yes complex part of
RAVE complex part of25 BRENDA localization in branch, click for list of all
ribulose bisphosphate carboxylase complex part of
sarcoplasm is a24 BRENDA localization in branch, click for list of all
sarcosine oxidase complex part of
SCAR complex part of
scintillon part of23 BRENDA localization in branch, click for list of all
Scrib-APC complex part of
Scrib-APC-beta-catenin complex part of
serine-pyruvate aminotransferase complex part of
Sid2-Mob1 complex part of
signal recognition particle part of22 BRENDA localization in branch, click for list of all
Ski complex part of21 BRENDA localization in branch, click for list of all
SMN-Sm protein complex part of
SNARE complex part of20 BRENDA localization in branch, click for list of all
spectrosome part of
sulfate adenylyltransferase complex (ATP) part of
thioglucosidase complex part of
translation initiation complex part of19 BRENDA localization in branch, click for list of all
translation initiation ternary complex part of
translation preinitiation complex part of
translation release factor complex part of
transnitrosylase complex part of
tricarboxylic acid cycle enzyme complex part of
type I site-specific deoxyribonuclease complex part of
type II site-specific deoxyribonuclease complex part of
type III site-specific deoxyribonuclease complex part of
type IV site-specific deoxyribonuclease complex part of
UFD1-NPL4 complex part of
urease complex part of17 BRENDA localization in branch, click for list of all
vacuolar transporter chaperone complex part of
vacuole part of16 BRENDA localization in branch, click for list of all
VCP-NSFL1C complex part of
viral assembly compartment part of
viral assembly intermediate part of
WASH complex part of
yolk part of
deep fiber is a
dense fibrillar component is a245 BRENDA localization in branch, click for list of all
dense nuclear body is a
dinoflagellate antapex is a
dinoflagellate apex is a
dinoflagellate epicone is a
dinoflagellate hypocone is a
DNA replication termination region is a
eisosome is a244 BRENDA localization in branch, click for list of all
endonuclear canal is a243 BRENDA localization in branch, click for list of all
endospore core is a
ensheathing process is a
envelope is a242 BRENDA localization in branch, click for list of all
epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a
extra-invasive hyphal space is a
extracellular matrix is a241 BRENDA localization in branch, click for list of all
extracellular region is a226 BRENDA localization in branch, click for list of all
extrachromosomal circular DNA is a208 BRENDA localization in branch, click for list of all
extrachromosomal DNA is a207 BRENDA localization in branch, click for list of all
extrinsic component of membrane is a
fibrillar center is a
Flemming body is a
gas vesicle shell is a
germ tube is a205 BRENDA localization in branch, click for list of all
granular component is a204 BRENDA localization in branch, click for list of all
half bridge of spindle pole body is a
host cellular component is a
incipient cellular bud site is a
inclusion body is a189 BRENDA localization in branch, click for list of all
inner membrane pellicle complex is a
inner plaque of spindle pole body is a
intermediate layer of spindle pole body is a
intracellular immature spore is a
intrinsic component of membrane is a
investment cone is a
lateral element is a
lateral loop is a
lateral part of cell is a
leaflet of membrane bilayer is a
manchette is a180 BRENDA localization in branch, click for list of all
median body is a
membrane is a179 BRENDA localization in branch, click for list of all
membrane-enclosed lumen is a
metaphase plate is a119 BRENDA localization in branch, click for list of all
microtubule bundle is a
microtubule end is a118 BRENDA localization in branch, click for list of all
microtubule organizing center is a116 BRENDA localization in branch, click for list of all
midbody is a110 BRENDA localization in branch, click for list of all
myelin sheath is a109 BRENDA localization in branch, click for list of all
neck portion of tanycyte is a
nucleoid is a108 BRENDA localization in branch, click for list of all
nucleus lagging edge is a
nucleus leading edge is a
oral apparatus is a106 BRENDA localization in branch, click for list of all
organelle is a105 BRENDA localization in branch, click for list of all
pellicle is a17 BRENDA localization in branch, click for list of all
periplasmic space is a16 BRENDA localization in branch, click for list of all
photoreceptor inner segment is a15 BRENDA localization in branch, click for list of all
polar tube is a14 BRENDA localization in branch, click for list of all
postsynapse is a
presynapse is a
site of polarized growth is a
somatodendritic compartment is a
sperm head is a12 BRENDA localization in branch, click for list of all
sperm head-tail coupling apparatus is a
sporoplasm is a
supramolecular complex is a11 BRENDA localization in branch, click for list of all
symplast is a10 BRENDA localization in branch, click for list of all
synapse is a9 BRENDA localization in branch, click for list of all
tail portion of tanycyte is a
thylakoid is a2 BRENDA localization in branch, click for list of all
Yb body is a
intracellular is a70 BRENDA localization in branch, click for list of all
other organism part is a
protein-containing complex is a46 BRENDA localization in branch, click for list of all
virion is a8 BRENDA localization in branch, click for list of all
molecular_function is a