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Gene ontology
Version 2014-12-22
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Details for super elongation complex
super elongation complex
Gene ontology ID
GO:0032783
Definition
A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae
Synonyms
1. ELL-EAF complex
2. ELL-EAF-EBP complex
References
1. PMID 17150956
2. PMID 30102332
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