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Gene ontology
Version 2014-12-22
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Details for TIM22 mitochondrial import inner membrane insertion complex
Gene ontology ID
GO:0042721
Definition
A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12
Synonyms
1. mitochondrial inner membrane protein insertion complex
2. mitochondrial protein translocase complex
3. Tim22 complex
References
1. PMID 12191765
2. PMID 27554484
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