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Gene ontology
Version 2014-12-22
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Details for TIM23 mitochondrial import inner membrane translocase complex
7.4.2.3
Gene ontology ID
GO:0005744
Definition
The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor
Comment
See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
Synonyms
1. mitochondrial inner membrane pre-sequence translocase complex
2. mitochondrial inner membrane presequence translocase complex
3. mitochondrial inner membrane translocase complex
4. Tim23 complex
References
1. EC 7.4.2.3
2. PMID 27554484
3. PMID 8851659
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