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BRENDA support

Ontology explorer

Gene ontology
Version 2014-12-22
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Details for HFE-transferrin receptor complex
Gene ontology ID
GO:1990712
Definition
A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription
References
1. GOC: BHF
2. GOC: kom
3. PMID 25147378
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