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Gene ontology
Version 2014-12-22
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Details for Wnt-Frizzled-LRP5/6 complex
Gene ontology ID
GO:1990851
Definition
A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6
Comment
Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form.
Synonyms
1. Frizzled-LRP5/6 complex
2. Fz/Wnt/LRP6 complex
3. Wnt receptor complex
4. WNT-FZD-LRP5 complex
5. Wnt-FZD-LRP5/6 trimeric complex
6. WNT-FZD-LRP6 complex
7. Wnt-induced Frizzled-LRP5/6 complex
8. Wnt.Fz.LRP ternary complex
References
1. GOC: bf
2. GOC: PARL
3. PMID 11448771
4. PMID 20093360
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