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Gene ontology
Version 2014-12-22
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Details for ciliary basal body
ciliary basal body
Gene ontology ID
GO:0036064
Definition
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport
Comment
In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
Synonyms
1. basal body
2. cilial basal body
3. cilium basal body
4. microtubule basal body
References
1. GOC: cilia
2. GOC: clt
3. PMID 21750193
4. NIF Subcellular: sao11978067
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