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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for filopodium
filopodiumfilopodium
Gene ontology ID
GO:0030175
Definition
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft
Comment
A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.
References
1. GOC: mah
2. GOC: pr
3. ISBN 0815316194
4. NIF Subcellular: sao1046371754
5. Wikipedia: Filopodia
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