Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

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Localization

Enzyme

44 different search results found

Details for Derlin-1 retrotranslocation complex

Gene ontology ID

GO:0036513

Definition

A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel

Comment

The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.

Synonyms

1. Derlin-1 complex
2. Derlin-1 protein dislocation complex
3. Derlin-1 retro-translocation complex
4. Derlin-1 retrotranslocon
5. ERAD protein dislocation complex

References

1. GOC: bf
2. GOC: PARL
3. PMID 15215856
4. PMID 16186510

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

cellular_component is a

cellular anatomical entity is a

peg and socket contact is a

inner dense plaque of desmosome part of

cell periphery is a

651 BRENDA localization in branch, click for list of all

extrinsic component of external side of cell outer membrane part of

plasma membrane part of

611 BRENDA localization in branch, click for list of all

endomembrane system

130 BRENDA localization in branch, click for list of all

Hrd1p ubiquitin ligase ERAD-L complex is a

oligosaccharyltransferase II complex is a

clathrin coat of trans-Golgi network vesicle part of

nuclear pore part of

nuclear pore nuclear basket part of

nuclear outer membrane-endoplasmic reticulum membrane network part of

endoplasmic reticulum membrane part of

1 BRENDA localization in branch, click for list of all

Derlin-1 retrotranslocation complex part of

endoplasmic reticulum palmitoyltransferase complex part of

glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex part of

chromaffin granule membrane part of

12 BRENDA localization in branch, click for list of all

neuronal dense core vesicle is a

alveolar lamellar body is a

zymogen granule is a

transport vesicle part of

64 BRENDA localization in branch, click for list of all

cytoplasmic side of transport vesicle membrane part of

ER to Golgi transport vesicle membrane is a

exocytic vesicle membrane is a

integral component of external side of plasma membrane is a

granulocyte macrophage colony-stimulating factor receptor complex part of

Tree view

Gene ontology

biological_process is a

cellular_component is a

cell

cellular anatomical entity is a

A band

727 BRENDA localization in branch, click for list of all

acroblast

acrosomal matrix is a

724 BRENDA localization in branch, click for list of all

actin body is a

actin cap

723 BRENDA localization in branch, click for list of all

actin filament branch point is a

actin filament bundle is a

actin fusion focus is a

actin wave is a

actomyosin is a

717 BRENDA localization in branch, click for list of all

actomyosin contractile ring, distal actin filament layer is a

actomyosin contractile ring, intermediate layer is a

actomyosin contractile ring, proximal layer is a

alae of collagen and cuticulin-based cuticle extracellular matrix is a

annular furrow extracellular matrix is a

annuli extracellular matrix is a

apical complex is a

716 BRENDA localization in branch, click for list of all

apical cytoplasm is a

apical lamina of hyaline layer is a

apical part of cell is a

711 BRENDA localization in branch, click for list of all

ascus epiplasm is a

assemblon

axon collateral is a

709 BRENDA localization in branch, click for list of all

axon hillock is a

708 BRENDA localization in branch, click for list of all

axon initial segment is a

707 BRENDA localization in branch, click for list of all

axonemal basal plate is a

axonemal central apparatus is a

axonemal outer doublet is a

702 BRENDA localization in branch, click for list of all

axoneme

701 BRENDA localization in branch, click for list of all

bacterial biofilm matrix surface is a

bacterial-type flagellum basal body is a

bacterial-type flagellum filament is a

bacterial-type flagellum hook is a

bacterial-type flagellum hook-filament junction is a

basal labyrinth is a

basal layer of collagen and cuticulin-based cuticle extracellular matrix is a

basal part of cell is a

basolateral cytoplasm is a

bilobe structure is a

blood microparticle is a

Casparian strip is a

cell body

696 BRENDA localization in branch, click for list of all

cell division site is a

693 BRENDA localization in branch, click for list of all

cell junction is a

688 BRENDA localization in branch, click for list of all

cell leading edge is a

cell periphery is a

cell cortex part of

38 BRENDA localization in branch, click for list of all

external encapsulating structure part of

25 BRENDA localization in branch, click for list of all

plasma membrane part of

cell envelope

133 BRENDA localization in branch, click for list of all

cell trailing edge membrane part of

cellular bud membrane part of

cornified envelope is a

132 BRENDA localization in branch, click for list of all

cytoplasmic side of plasma membrane part of

cytoproct

cytostome

endomembrane system

clathrin-coated pit part of

endoplasmic reticulum part of

endosome

50 BRENDA localization in branch, click for list of all

Golgi apparatus part of

39 BRENDA localization in branch, click for list of all

cis-Golgi network part of

7 BRENDA localization in branch, click for list of all

clathrin coat of trans-Golgi network vesicle part of

AP-1 adaptor complex part of

6 BRENDA localization in branch, click for list of all

COPI vesicle coat part of

exomer complex part of

5 BRENDA localization in branch, click for list of all

GARP complex part of

4 BRENDA localization in branch, click for list of all

Golgi apparatus subcompartment part of

Golgi cisterna is a

Golgi stack is a

trans-Golgi network is a

2 BRENDA localization in branch, click for list of all

Golgi lumen part of

Golgi membrane part of

Golgi transport complex part of

Golgi-associated vesicle lumen part of

inositol phosphoceramide synthase complex part of

RIC1-RGP1 guanyl-nucleotide exchange factor complex part of

TRAPPIII protein complex part of

nuclear envelope part of

30 BRENDA localization in branch, click for list of all

microtubule organizing center attachment site part of

nuclear envelope lumen part of

nuclear membrane part of

3 BRENDA localization in branch, click for list of all

5-lipoxygenase complex part of

nuclear inner membrane is a

nuclear outer membrane is a

nuclear membrane protein complex part of

nuclear pore part of

cytoplasmic side of nuclear pore part of

nuclear pore central transport channel part of

nuclear pore cytoplasmic filaments part of

nuclear pore inner ring part of

nuclear pore linkers part of

nuclear pore nuclear basket part of

nuclear pore outer ring part of

nuclear pore transmembrane ring part of

nucleoplasmic side of nuclear pore part of

nucleoplasmic reticulum part of

nuclear outer membrane-endoplasmic reticulum membrane network part of

annulate lamellae part of

endoplasmic reticulum membrane part of

cytoplasmic side of endoplasmic reticulum membrane part of

Derlin-1 retrotranslocation complex part of

Derlin-1-VIMP complex part of

endoplasmic reticulum palmitoyltransferase complex part of

serine C-palmitoyltransferase complex is a

glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex part of

intrinsic component of endoplasmic reticulum membrane part of

Ire1 complex part of

IRE1-TRAF2-ASK1 complex part of

lumenal side of endoplasmic reticulum membrane part of

signal peptidase complex part of

Nem1-Spo7 phosphatase complex part of

omegasome

21 BRENDA localization in branch, click for list of all

retromer complex part of

secretory granule part of

20 BRENDA localization in branch, click for list of all

acrosomal vesicle is a

acrosomal lumen part of

acrosomal membrane part of

17 BRENDA localization in branch, click for list of all

inner acrosomal membrane part of

outer acrosomal membrane part of

protein C inhibitor-acrosin complex part of

azurophil granule is a

14 BRENDA localization in branch, click for list of all

chromaffin granule is a

13 BRENDA localization in branch, click for list of all

chromaffin granule lumen part of

chromaffin granule membrane part of

cortical granule is a

11 BRENDA localization in branch, click for list of all

dense core granule is a

10 BRENDA localization in branch, click for list of all

ficolin-1-rich granule is a

insulin-responsive compartment is a

9 BRENDA localization in branch, click for list of all

lamellar body is a

8 BRENDA localization in branch, click for list of all

alveolar lamellar body membrane part of

mucin granule is a

mucocyst

platelet alpha granule is a

platelet dense granule is a

secretory granule lumen part of

secretory granule membrane part of

ficolin-1-rich granule membrane is a

specific granule membrane is a

tertiary granule membrane is a

zymogen granule membrane is a

specific granule is a

tertiary granule is a

Weibel-Palade body is a

zymogen granule is a

spitzenkorper part of

transport vesicle part of

clathrin-sculpted acetylcholine transport vesicle is a

clathrin-sculpted glutamate transport vesicle is a

clathrin-sculpted monoamine transport vesicle is a

COPI-coated Golgi to ER transport vesicle is a

COPI-coated inter-Golgi transport vesicle is a

exocytic vesicle is a

trans-Golgi network transport vesicle is a

transport vesicle lumen part of

transport vesicle membrane part of

COPII vesicle coat part of

external side of plasma membrane part of

integral component of periplasmic side of plasma membrane is a

extrinsic component of plasma membrane part of

growth cone membrane part of

immunological synapse part of

62 BRENDA localization in branch, click for list of all

intrinsic component of plasma membrane part of

anchored component of plasma membrane is a

integral component of plasma membrane is a

acetylcholine-gated channel complex part of

activin receptor complex part of

alphav-beta5 integrin-vitronectin complex part of

BMP receptor complex part of

CD40 receptor complex part of

ciliary neurotrophic factor receptor complex part of

Cus cation efflux complex part of

EFF-1 complex part of

EmrE multidrug transporter complex part of

enzyme IIA-maltose transporter complex part of

G protein-coupled receptor complex part of

glycine-gated chloride channel complex part of

glycoprotein Ib-IX-V complex part of

granulocyte macrophage colony-stimulating factor receptor complex part of

high molecular weight kininogen receptor complex part of

histamine-gated chloride channel complex part of

insulin receptor complex part of

integral component of muscle cell projection membrane is a

integrin complex part of

interleukin-1 receptor complex part of

interleukin-12 receptor complex part of

interleukin-13 receptor complex part of

interleukin-18 receptor complex part of

interleukin-2 receptor complex part of

interleukin-20 receptor complex part of

interleukin-23 receptor complex part of

interleukin-28 receptor complex part of

interleukin-3 receptor complex part of

interleukin-4 receptor complex part of

interleukin-5 receptor complex part of

interleukin-6 receptor complex part of

interleukin-9 receptor complex part of

inward rectifying potassium channel part of

ionotropic glutamate receptor complex part of

maltose transport complex part of

membrane attack complex part of

NADPH oxidase complex part of

NarGHI complex part of

oncostatin-M receptor complex part of

plasma membrane proton-transporting V-type ATPase, V0 domain part of

plasma membrane proton-transporting V-type ATPase, V1 domain part of

platelet-derived growth factor receptor-ligand complex part of

potassium:proton exchanging ATPase complex part of

pre-T cell receptor complex part of

SC5b-7 complex part of

sodium:potassium-exchanging ATPase complex part of

spanning component of plasma membrane is a

sucrase-isomaltase complex part of

transmembrane collagen trimer part of

type I interferon receptor complex part of

voltage-gated potassium channel complex part of

voltage-gated sodium channel complex part of

intrinsic component of plasma membrane of cell tip is a

lateral plasma membrane part of

53 BRENDA localization in branch, click for list of all

mesosome

52 BRENDA localization in branch, click for list of all

orthogonal array part of

51 BRENDA localization in branch, click for list of all

phagocytic cup part of

plasma membrane protein complex part of

49 BRENDA localization in branch, click for list of all

plasma membrane region part of

plasma membrane respirasome part of

plasma membrane-derived thylakoid lumen part of

porosome

sarcolemma is a

sperm plasma membrane is a

tetraspanin-enriched microdomain part of

unencapsulated part of cell

cell plate is a

476 BRENDA localization in branch, click for list of all

cell pole

475 BRENDA localization in branch, click for list of all

cell projection is a

cell septum is a

468 BRENDA localization in branch, click for list of all

cell surface is a

467 BRENDA localization in branch, click for list of all

cell tip

cell trailing edge is a

cellular bud is a

central element is a

465 BRENDA localization in branch, click for list of all

central plaque of spindle pole body is a

centriolar satellite is a

centrosomal corona is a

chiasma

464 BRENDA localization in branch, click for list of all

chromatin

463 BRENDA localization in branch, click for list of all

chromosomal region is a

446 BRENDA localization in branch, click for list of all

cnida

compact myelin is a

440 BRENDA localization in branch, click for list of all

concave side of sperm head is a

cone matrix sheath is a

contractile ring is a

439 BRENDA localization in branch, click for list of all

cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a

costamere

cytoophidium is a

438 BRENDA localization in branch, click for list of all

cytoplasm

437 BRENDA localization in branch, click for list of all

deep fiber is a

dense fibrillar component is a

250 BRENDA localization in branch, click for list of all

dense nuclear body is a

dinoflagellate antapex is a

dinoflagellate apex is a

dinoflagellate epicone is a

dinoflagellate hypocone is a

DNA replication termination region is a

eisosome

249 BRENDA localization in branch, click for list of all

endonuclear canal is a

248 BRENDA localization in branch, click for list of all

endospore core is a

ensheathing process is a

envelope

247 BRENDA localization in branch, click for list of all

epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a

extracellular matrix is a

246 BRENDA localization in branch, click for list of all

extracellular region is a

230 BRENDA localization in branch, click for list of all

extrachromosomal circular DNA is a

212 BRENDA localization in branch, click for list of all

extrachromosomal DNA is a

211 BRENDA localization in branch, click for list of all

extrinsic component of membrane is a

fibrillar center is a

Flemming body is a

gas vesicle shell is a

germ tube

209 BRENDA localization in branch, click for list of all

granular component is a

208 BRENDA localization in branch, click for list of all

half bridge of spindle pole body is a

host cellular component is a

incipient cellular bud site is a

inclusion body is a

193 BRENDA localization in branch, click for list of all

inner membrane pellicle complex is a

inner plaque of spindle pole body is a

intermediate layer of spindle pole body is a

intracellular immature spore is a

intrinsic component of membrane is a

investment cone is a

lateral element is a

lateral loop is a

lateral part of cell is a

leaflet of membrane bilayer is a

manchette

183 BRENDA localization in branch, click for list of all

median body is a

membrane

182 BRENDA localization in branch, click for list of all

membrane-enclosed lumen is a

metaphase plate is a

119 BRENDA localization in branch, click for list of all

microtubule bundle is a

microtubule end is a

118 BRENDA localization in branch, click for list of all

microtubule organizing center is a

116 BRENDA localization in branch, click for list of all

midbody

107 BRENDA localization in branch, click for list of all

myelin sheath is a

106 BRENDA localization in branch, click for list of all

neck portion of tanycyte is a

nucleoid

105 BRENDA localization in branch, click for list of all

nucleus lagging edge is a

nucleus leading edge is a

oral apparatus is a

103 BRENDA localization in branch, click for list of all

organelle

102 BRENDA localization in branch, click for list of all

pellicle

periplasmic space is a

photoreceptor inner segment is a

polar tube is a

site of polarized growth is a

somatodendritic compartment is a

sperm head is a

sperm head-tail coupling apparatus is a

sporoplasm is a

subapical part of cell is a

supramolecular complex is a

symplast

tail portion of tanycyte is a

thylakoid

Yb body

intracellular is a

81 BRENDA localization in branch, click for list of all

other organism part is a

protein-containing complex is a

55 BRENDA localization in branch, click for list of all

virion

molecular_function is a

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Release 2023.1 (January 2023)