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Gene ontology
Version 2014-12-22
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Details for desmosome
desmosome
Gene ontology ID
GO:0030057
Definition
A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism
Synonyms
1. macula adherens
2. spot desmosome
References
1. GOC: mah
2. GOC: mtg muscle
3. ISBN 0815332181
4. Wikipedia: Desmosome
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