Details for 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex
1.2.4.4Gene ontology ID
GO:0017086
Definition
A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate
Synonyms
1. BCADH
2. branched-chain alpha-ketoacid dehydrogenase complex
References
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tissue/ enzyme/ localization link to BRENDA
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