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Gene ontology
Version 2014-12-22
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Details for peroxiredoxin activity
1.11.1.15
Gene ontology ID
GO:0051920
Definition
Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH
Comment
Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.
Synonyms
1. AhpC activity
2. alkyl hydroperoxide reductase C22 activity
3. PRDX activity
4. Prx activity
5. thiol-containing-reductant:hydroperoxide oxidoreductase activity
References
1. EC 1.11.1.15
2. RHEA: 10008
3. MetaCyc 1.11.1.15-RXN
4. Reactome: R-HSA-1222431 "Peroxynitrite is reduced to nitrite by AhpC"
5. Reactome: R-HSA-1222755 "Peroxynitrite is reduced to nitrite by Tpx"
6. Reactome: R-HSA-1500804 "Peroxynitrite is reduced by AhpE"
Legend
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is a part of the parent element
is related to the parent element
derives from the parent element
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