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Gene ontology
Version 2014-12-22
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Details for methylthiol:coenzyme M methyltransferase activity
2.1.1.251
Gene ontology ID
GO:0044683
Definition
Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM
Comment
This reaction is achieved by the catalysis of two successive steps carried out by the same enzyme - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, EC:2.1.1.90, methanol-corrinoid protein Co-methyltransferase, and EC:2.1.1.246, methylated methanol-specific corrinoid protein:coenzyme M methyltransferase). The cobalt is oxidized during methylation from the Co(I) state to the Co(III) state, and is reduced back to the Co(I) form during demethylation.
Synonyms
1. methylthiol:coenzyme M methyl transferase activity
References
1. MetaCyc RXN-8125
2. PMID 9371433
3. EC 2.1.1.251
4. RHEA: 32667
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is a part of the parent element
is related to the parent element
derives from the parent element
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Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
transferase activity is a
transferase activity, transferring one-carbon groups is a
methyltransferase activity is a
methylthiol:coenzyme M methyltransferase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
Atg8 ligase activity is a
CDP-alcohol phosphotransferase activity is a
glucanosyltransferase activity is a
Kdo transferase activity is a
mannosylphosphate transferase activity is a
molybdopterin molybdotransferase activity is a
transferase activity, transferring acyl groups is a
transferase activity, transferring aldehyde or ketonic groups is a
transferase activity, transferring alkyl or aryl (other than methyl) groups is a
transferase activity, transferring glycosyl groups is a
transferase activity, transferring nitrogenous groups is a
transferase activity, transferring one-carbon groups is a
carboxyl- or carbamoyltransferase activity is a
hydroxymethyl-, formyl- and related transferase activity is a
methyltransferase activity is a
(R)-reticuline 7-O-methyltransferase activity is a
(S)-reticuline 7-O-methyltransferase activity is a
1-hydroxy-6-methoxypyrene methyltransferase activity is a
1-hydroxypyrene methyltransferase activity is a
1-phenanthrol methyltransferase activity is a
12-demethyl-elloramycin C12a O-methyltransferase activity is a
2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity is a
2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity is a
2-polyprenyl-6-hydroxyphenol methylase activity is a
3',4',5'-trimethylmyricetin 3-O-methyltransferase activity is a
3',4',5'-trimethylmyricetin 7-O-methyltransferase activity is a
3'-O-methyltricetin O methyl transferase activity is a
3,5-dihydroxyanisole O-methyltransferase activity is a
3,5-dimethoxyphenol O-methyltransferase activity is a
3-aminomethylindole N-methyltransferase activity is a
3-methoxy-5-hydroxytoluene O-methyltransferase activity is a
3-methylquercetin 3'-O-methyltransferase activity is a
4,5-dihydroxybenzo(a)pyrene methyltransferase activity is a
4-hydroxytryptamine 4-phosphate methyltransferase activity is a
5,10-methylenetetrahydrofolate-dependent methyltransferase activity is a
5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity is a
5-methyl-phenazine-1-carboxylate N-methyltransferase activity is a
5-methyltetrahydrofolate-dependent methyltransferase activity is a
5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity is a
5-n-alk(en)ylresorcinol O-methyltransferase activity is a
6a-hydroxymaackiain-3-O-methyltransferase activity is a
7,8,4'-trihydroxyflavone methyltransferase activity is a
7-methylmyricetin 4'-O-methyltransferase activity is a
8-demethylnovobiocic acid C8-methyltransferase activity is a
adrenaline O-methyltransferase activity is a
aminomethyltransferase activity is a
apigenin 7-O-methyltransferase activity is a
bixin methyltransferase activity is a
C-methyltransferase activity is a
C4-demethylase activity is a
C4-methyltransferase activity is a
caffeoylglucose 3-O-methyltransferase activity is a
cirsimaritin 4'-O-methyltransferase activity is a
cobalt-factor II C20-methyltransferase activity is a
cobalt-precorrin-3 C17-methyltransferase activity is a
cobalt-precorrin-5B C1-methyltransferase activity is a
cobalt-precorrin-6B C5-methyltransferase activity is a
cobalt-precorrin-7 C15-methyltransferase activity is a
corydaline synthase activity is a
daphnetin-8-O-methyltransferase activity is a
demethylmenaquinone methyltransferase activity is a
demethylrebeccamycin--D-glucose O-methyltransferase activity is a
dimethyl selenide methyltransferase activity is a
dimethylamine methyltransferase activity is a
dimethylarsinite methyltransferase activity is a
dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity is a
dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity is a
dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity is a
eriodictyol 3'-O-methyltransferase activity is a
eriodictyol 4'-O-methyltransferase activity is a
erythromycin C 3''-o-methyltransferase activity is a
erythromycin D 3''-o-methyltransferase activity is a
flavanone 4'-O-methyltransferase activity is a
genkwanin 4'-O-methyltransferase activity is a
gibberellin A20 carboxyl methyltransferase activity is a
gibberellin A34 carboxyl methyltransferase activity is a
gibberellin A4 carboxyl methyltransferase activity is a
gibberellin A9 carboxyl methyltransferase activity is a
gossypetin 8-methyl ester 3'-O-methyltransferase activity is a
hydrogen selenide methyltransferase activity is a
hydroxyneurosporene-O-methyltransferase activity is a
indole acetic acid carboxyl methyltransferase activity is a
indole-3-acetate carboxyl methyltransferase activity is a
isorhamnetin 3-O-methyltransferase activity is a
isoscopoletin-O-methyltransferase activity is a
juvenile hormone acid methyltransferase activity is a
kaempferide 3-O-methyltransferase activity is a
kaempferide 7-O-methyltransferase activity is a
kaempferol 3-O-methyltransferase activity is a
L-dopa O-methyltransferase activity is a
ladanein 6-O-methyltransferase activity is a
laricitrin 4'-O-methyltransferase activity is a
malonyl-CoA methyltransferase activity is a
methaneselenol methyltransferase activity is a
methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity is a
methanol-specific methylcobalamin:coenzyme M methyltransferase activity is a
methyl jasmonate methylesterase activity is a
methylamine-specific methylcobalamin:coenzyme M methyltransferase activity is a
methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity is a
methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity is a
methylthiol:coenzyme M methyltransferase activity is a
monomethylamine methyltransferase activity is a
mycinamicin VI 2''-O-methyltransferase activity is a
myricetin 7-O-methyltransferase activity is a
N-methyl-3-aminomethylindole N-methyltransferase activity is a
N-methyltransferase activity is a
naringenin 7-O-methyltransferase activity is a
norbixin methyltransferase activity is a
O-methyltransferase activity is a
orcinol O-methyltransferase activity is a
P-methyltransferase activity is a
paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity is a
patuletin 3'-O-methyltransferase activity is a
phloroglucinol O-methyltransferase activity is a
precorrin-6A synthase (deacetylating) activity is a
protein-(glutamine-N5) methyltransferase activity is a
quercetin 3'-O-methyltransferase activity is a
quercetin 7-O-methyltransferase activity is a
resveratrol 3,5-O-dimethyltransferase activity is a
rhamnetin 3'-O-methyltransferase activity is a
rhamnetin 3-O-methyltransferase activity is a
rhamnetin 4'-O-methyltransferase activity is a
S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity is a
S-adenosyl-L-methionine:eugenol-O-methyltransferase activity is a
S-adenosylmethionine-dependent methyltransferase activity is a
S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity is a
S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity is a
S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity is a
S-methyltransferase activity is a
scutellarein 7-methyl ether 4'-O-methyltransferase activity is a
scutellarein 7-methyl ether 6-O-methyltransferase activity is a
Se-methyltransferase activity is a
selenol Se-methyltransferase activity is a
sterol 24C methyltransferase activity is a
syringetin 3-O-methyltransferase activity is a
syringetin 7-O-methyltransferase activity is a
tetracenomycin B3 8-O-methyl transferase activity is a
theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity is a
thiocyanate methyltransferase activity is a
TRIBOA-glucoside methyltransferase activity is a
tricaffeoyl spermidine O-methyltransferase activity is a
tricetin O-methytransferase activity is a
trimethylamine methyltransferase activity is a
[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity is a
transferase activity, transferring phosphorus-containing groups is a
transferase activity, transferring selenium-containing groups is a
transferase activity, transferring sulfur-containing groups is a
UDP-L-rhamnose synthase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a