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Gene ontology
Version 2014-12-22
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Details for long-chain-3-hydroxyacyl-CoA dehydrogenase activity
1.1.1.211
Gene ontology ID
GO:0016509
Definition
Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22
Comment
Also see '3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857'.
Synonyms
1. beta-hydroxyacyl-CoA dehydrogenase activity
2. LCHAD
3. long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity
4. long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity
References
1. EC 1.1.1.211
2. GOC: pde
3. MetaCyc 1.1.1.211-RXN
4. Reactome: R-HSA-548818 "HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA"
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