5.1.3.14Gene ontology ID
GO:0008761
Definition
Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine
Synonyms
1. UDP-GlcNAc-2-epimerase activity
2. UDP-N-acetyl-D-glucosamine 2-epimerase activity
3. UDP-N-acetylglucosamine 2'-epimerase activity
4. uridine diphosphate-N-acetylglucosamine-2'-epimerase activity
5. uridine diphospho-N-acetylglucosamine 2'-epimerase activity
6. uridine diphosphoacetylglucosamine 2'-epimerase activity
References
1. EC 5.1.3.142. MetaCyc UDPGLCNACEPIM-RXN3. Reactome: R-HSA-4085021 "GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP"
4. Reactome: R-HSA-4088338 "Defective GNE does not hydrolyse UDP-GlcNAc"
5. RHEA: 17213
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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at least 1 tissue/ enzyme/ localization link in this branch
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tissue/ enzyme/ localization link to BRENDA