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Gene ontology
Version 2014-12-22
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Details for DNA-3-methyladenine glycosylase activity
3.2.2.20, 3.2.2.21
Gene ontology ID
GO:0008725
Definition
Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site
Synonyms
1. 3-methyladenine DNA glycosylase I
2. alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
3. deoxyribonucleate 3-methyladenine glycosidase I
4. DNA glycosidase I activity
5. DNA-3-methyladenine glycosidase I activity
6. DNA-3-methyladenine glycosylase I activity
References
1. EC 3.2.2.20
2. GOC: elh
3. PMID 10872450
4. PMID 9224623
5. EC 3.2.2.21
6. MetaCyc 3.2.2.20-RXN
7. MetaCyc 3.2.2.21-RXN
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