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Gene ontology
Version 2014-12-22
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Details for isoleucine-tRNA ligase activity
6.1.1.5
Gene ontology ID
GO:0004822
Definition
Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+)
Synonyms
1. isoleucine translase activity
2. isoleucine-transfer RNA ligase activity
3. isoleucine-tRNA synthetase activity
4. isoleucyl-transfer ribonucleate synthetase activity
5. isoleucyl-transfer RNA synthetase activity
6. isoleucyl-tRNA synthetase activity
7. L-isoleucine:tRNAIle ligase (AMP-forming)
References
1. EC 6.1.1.5
2. RHEA: 11060
3. KEGG REACTION: R03656
4. MetaCyc ISOLEUCINE--TRNA-LIGASE-RXN
5. Reactome: R-HSA-379893 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate"
6. Reactome: R-HSA-380176 "isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate"
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