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Gene ontology
Version 2014-12-22
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Details for glutathione-disulfide reductase activity
1.8.1.7
Gene ontology ID
GO:0004362
Definition
Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+
Comment
Note that this function was formerly EC:1.6.4.2.
Synonyms
1. glutathione reductase (NADPH) activity
2. glutathione reductase activity
3. glutathione S-reductase activity
4. glutathione-disulphide reductase activity
5. glutathione:NADP+ oxidoreductase activity
6. GSH reductase activity
7. GSSG reductase activity
8. NADPH-glutathione reductase activity
9. NADPH-GSSG reductase activity
10. NADPH:oxidized-glutathione oxidoreductase activity
11. oxidized glutathione reduction
References
1. EC 1.8.1.7
2. ISBN 0198506732
3. MetaCyc GLUTATHIONE-REDUCT-NADPH-RXN
4. Reactome: R-HSA-3323079 "GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+"
5. Reactome: R-HSA-71682 "glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+"
6. RHEA: 11740
Legend
is an element of the parent element
is a part of the parent element
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Gene ontology
biological_process is a
cellular process is a
cellular detoxification is a
cellular oxidant detoxification is a
antioxidant activity part of
glutathione-disulfide reductase activity is a
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular detoxification of aldehyde is a
cellular detoxification of cadmium ion is a
cellular detoxification of copper ion is a
cellular detoxification of fluoride is a
cellular detoxification of nitrogen compound is a
cellular oxidant detoxification is a
antioxidant activity part of
glutathione dehydrogenase (ascorbate) activity is a
glutathione-disulfide reductase activity is a
peroxidase activity is a
peroxiredoxin activity is a
sulfiredoxin activity is a
superoxide dismutase activity is a
superoxide reductase activity is a
thioredoxin-disulfide reductase activity is a
cellular detoxification of hydrogen peroxide is a
removal of superoxide radicals is a
toxic metabolite repair is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a