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Gene ontology
Version 2014-12-22
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Details for acetyl-CoA carboxylase activity
6.4.1.2
Gene ontology ID
GO:0003989
Definition
Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA
Synonyms
1. acetyl coenzyme A carboxylase activity
2. acetyl-CoA:carbon-dioxide ligase (ADP-forming)
References
1. EC 6.4.1.2
2. MetaCyc ACETYL-COA-CARBOXYLTRANSFER-RXN
3. Reactome: R-HSA-200555 "acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate"
4. Reactome: R-HSA-75851 "Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA"
5. Reactome: R-HSA-8876889 "Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA"
6. RHEA: 11308
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derives from the parent element
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